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ADORA2A Membrane Protein

ADORA2A Membrane Protein

Author: creative biolabs

ADORA2A Membrane Protein

ADORA2A is encoded by ADORA2A gene. It belongs to the G-protein-coupled receptor (GPCR) family which has been extensively studied during the past few decades because it offers numerous possibilities for therapeutic applications. It is one of the four subtypes of adenosine receptors (A1R, A2AR, A2BR, A3R). ADORA2A possess seven transmembrane alpha helices and uses adenosine as the preferred endogenous agonist. Meanwhile, its structure reveals a ligand binding pocket distinct from that of other structurally determined GPCRs.

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