american peptide amyloid beta 1 42
The molecular weight of amyloid β-protein (Aβ) is about 4kDa, which is hydrolyzed by β-amyloid precursor protein (APP) and secreted by cells. It has very strong neurotoxic effect after sedimentation in cell matrix. Amyloid-β (Aβ) is a polypeptide containing 39 to 43 amino acids produced by proteolysis of amyloid precursor protein (APP) by β- and γ-secretase.