The covalent binding ability of Michael receptor also brings a certain potential risk of genotoxicity (mutagenicity), so it is necessary to fully evaluate it. The AMES test is a wide range of genetic toxicity (mutagenicity) bioassay methods. The traditional AMES test prediction method is often based on chemical structure. Because it ignores the internal chemical process related to DNA reactivity, the prediction results are likely to lead to false Positive. Therefore CD BioSciences provides computational chemistry to solve the AMES test for you.