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Anti-AchR Recombinant Immunotoxin

Anti-AchR Recombinant Immunotoxin

Author: creative biolabs

Anti-AchR Recombinant Immunotoxin

35-scFv-ETA immunotoxin directs at fetal AchR, wherein the immunotoxin comprises a human scFv fragment based on a human autoantibody 35 and a pseudomonas exotoxin A. 35-scFv-ETA is the first cancer-directed immunotoxin with a fully human antibody moiety and the first IT targeting an antigen that is virtually specific for RMS. 35-scFv-ETA appears promising for further preclinical evaluation as a therapeutic tool against high-risk RMS.

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