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C9736H14863N2591O2855S78

C9736H14863N2591O2855S78

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Author: Creative BioMart
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C9736H14863N2591O2855S78

The product is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as Moroctocog alfa. Factor VIII is a blood coagulant factor involved in the intrinsic pathway to form fibrin, or a blood clot. The product is a first commercially available rFVIII-Fc fusion protein (rFVIIIFc) where the conjugated molecule of rFVIII to polyethylene glycol is covalently fused to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma protein. The B domain of factor VIII is deleted.

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Developing Effective Teams

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