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Changes to Chromosome Structure
Next Generation: HS.LS3.2 HS.LS3.2

Changes to Chromosome Structure

Author: Nathan Lampson

This lesson will identify how the structure of a chromosome can change and the implications that come from changes in chromosomes.

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Terms to Know

A genetic disorder caused by the deletion of a section of the 5th chromosome; cri-du-chat is French for “cry of the cat”. Cri-du-chat causes physical and cognitive abnormalities.


When part of a chromosome is deleted; sometimes it may not have any effect while other times it does.


Sequences of nucleotides are repeated multiple times, they haven’t been linked to disorders, but have been linked to cancers.


Looking at the number of chromosomes and their characteristics under a microscope, this is a critical tool in assessing genetic disorders in a developing embryo.


A chromosome abnormality that occurs when nonhomologous parts rearrange and fuse together.