Online College Courses for Credit

Chemistry Calculation

Chemistry Calculation

Author: Dynah Perry

Chemistry Calculation

Compared with traditional non-covalent inhibitors, covalent inhibitors can achieve higher binding affinity and longer residence time. These characteristics can be realized into lower doses, dosing frequency and systemic exposure of drugs. Therefore, many pharmaceutical companies have initiated drug development programs for covalent inhibitors of various enzymes. Once the ligand is docked into the binding site, the warhead will form a covalent bond with nearby amino acid residues. By designing inhibitors so that covalent bonds are only formed on non-catalytic residues with poor conservation, the target selectivity can be maximized.

See More
Fast, Free College Credit

Developing Effective Teams

Let's Ride
*No strings attached. This college course is 100% free and is worth 1 semester credit.

46 Sophia partners guarantee credit transfer.

299 Institutions have accepted or given pre-approval for credit transfer.

* The American Council on Education's College Credit Recommendation Service (ACE Credit®) has evaluated and recommended college credit for 33 of Sophia’s online courses. Many different colleges and universities consider ACE CREDIT recommendations in determining the applicability to their course and degree programs.