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Coronavirus Single Particle Analysis

Coronavirus Single Particle Analysis

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Author: Dynah Perry
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Coronavirus Single Particle Analysis

In recent years, with the advancement of electronic detectors, algorithms and other crucial factors, electron microscopy (EM) technology has been increasingly utilized to study the ultrastructure of macromolecules, cells and tissues. In particular, single-particle cryo-electron microscopy (Cryo-EM) has become a popular and effective method for studying the structure of biologically significant molecules (such as proteins and virus particles) at a near-atomic resolution to better understand the three-dimensional (3D) structure and function of biological macromolecules. Creative Biostructure, a professional contract service provider in the field of structural biology, hopes to apply years of expertise and experience in single-particle Cryo-EM technology to the structural analysis of coronavirus-related proteins and complexes to support the structure-based design of vaccines and antiviral drugs.

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