Homeostasis and Bone Remodeling

Homeostasis and Bone Remodeling

Author: Aaron Mullally

This lesson will define the role of bone remodeling in maintaining homeostasis in the body.

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  • Osteoblast

    A cell found in bones that builds bone tissue by secreting collagen into bone tissue spaces; the collagen binds to calcium and forms the tough tissue within bones.

  • Osteoclast

    A cell found in bones that secretes hydrochloric acid that breaks down bone the bonds between calcium and collagen; the calcium is released from bone.

  • Bone remodeling

    The process bones constantly undergo of taking away and building tissue; is controlled by mechanical stress and hormonal negative feedback loops.

  • Homeostasis

    The process of maintaining a stable internal environment.

  • Parathyroid hormone (PTH)

    A hormone that is secreted by the parathyroid glands that activates osteoclasts when our blood calcium levels are too low.

  • Calcitonin

    A hormone that is secreted by the thyroid gland that lowers osteoclast activity in proportion to osteoblast activity.