Online College Courses for Credit

Karyotype Activity

Karyotype Activity

Author: Beth Barsness
  1. Students will construct and analyze a karyotype.
  2. Students will identify homologous chromosome pairs by their length, centromere position, and banding pattern.
  3. Students will determine the sex of an individual from a karyotype.

The goals of this lesson are for students to understand how to create a karyotype from a chromosome spread and to be able to analyze a karyotype to determine an individual’s sex and health.

This lesson was written by Melanie Kennedy.

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Lesson Plan

This lesson plan can be downloaded to your computer as a PDF document. If you would like to edit this document for your classroom needs, go to the "Handouts and Materials" section and click on the corresponding link.


Source: Melanie Kennedy

Handouts and Materials

The following files can be downloaded to your computer:

Lesson Plan (Word document)

Karyotype Activity Handout (Word document) 

Human Karyotype Form (PDF document) 

Chromosomes Spreads (PDF document) 

Genetic Disorders Reading (Word document) 

Karyotype Answer Key (PDF document) 

Source: Melanie Kennedy