By the end of this lesson, you will be able to:
All cell membranes have a universal structure of a phospholipid bilayer with globular proteins interspersed throughout, much like a mosiac. Proteins can stick partly through the membrane (periperal) or go all the way through the membrane from one side to the other (transmembrane, peripheral). This tutorial goes through the history of the development of the Fluid Mosaic model to show how new information is incorporated into viable scientific explanations.
The biophysical properties of phospholipids and proteins can be seen in the way they form membranes. The video begins with a highlight of the historical development of the Fluid Mosaic model of the Cell Membrane. Emphasis is placed on the biophysical properties of these molecules. Any good scientific explanation continues to be modified as new information is learned. The video finishes with some relevant research published in June 2014.
Source: M. O'Mahony, open source figures
BioVisions, (Harvard University) has produced this animation "The Inner Life of the Cell".
Watch this - and find the references to the cell membrane structure and function within it.
Source: BioVisions, Harvard University
Fatty Acid Vesicle Formation
De novo vesicle formation from fatty acid micelles - Protons are represented by the small glowing spheres. Upon protonation, the micelle structure becomes more fluid and may allow for larger numbers of micelles to join together. Vesicle formation occurs by chance after the fatty acid sheet has reached a threshold surface area.
Source: Janet Iwasa, Harvard Animation Collections
This is the notes template for the lesson.
Source: M. O'Mahony, open source images
A great interactive simulation that explores the composition of the Cell Membrane. To to: