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Mutations

Mutations

Description:

To address GADOE Biology Curriculum:

SB2. Students will analyze how biological traits are passed on to successive generations.

d. Describe the relationships between changes in DNA and potential appearance of new traits including

Alterations during replication (Insertions, Deletions, Substitutions)

Mutagenic factors that can alter DNA (High energy radiation (x-rays and ultraviolet), Chemical)

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Tutorial

Vocabulary Accordion Book

Create a vocabulary accordion book of the following terms. Be sure to write the word and then use it in a biologically, contextual sentence.

  • DNA
  • trait
  • mutation
  • replication
  • insertion (w.r.t. nucleotides)
  • deletion (w.r.t. nucleotides)
  • substitution (w.r.t. nucleotides)
  • mutagenic factors

Mutations Slide Show

Look this over and take notes. It will be helpful.

Cancer Quest

Go to Cancer Quest's page on Mutations.  On the upper, left hand side there is a menu of sections. I would like for you to read through all parts of the following sections: introduction to mutations, types of mutations, causes of mutations, and mutation summary.  TAKE NOTES ON ALL SECTIONS.

Quad Comparison Chart

You will use this when you compare various types of genetic disorders that result from mutations. I will hand out two of these in class. This is here in case you need to print another.

Full Screen

Using the quad comparison chart

Go to Learn.Genetic - Genetic Disorders.  Click on Single Gene Disorders and choose 4 disorders to read about.  Fill out the first of the two quad comparison charts I gave you in class.  Click on the Chromosomal Abnormalities and choose 4 disorders ot read about.  Fill out the second of the two quad comparison charts I gave you in class.

Source: Learn.Genetics, University of Utah, Health Sciences

Nathan Lampson's SOPHIA tutorial

Go back to the main page for our Group and click on the tutorial titled "Mutations" by Nathan Lampson.  Watch his video AND TAKE NOTES.

Source: Nathan Lampson

Block Letter Tutorial

Use this template to construct your letter. I will give you a hard copy in class and this is here as a back-up.

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Main Assignment - Formal Letter to Your Mother

In addition to the accordion vocabulary book and the two quad comparisons you will TYPE formal letter to your mother explaining to her why learning about mutations is important.  Make sure you reference the language of the standard from the top of this tutorial.  You will need to talk about and support each idea in the standard; to use appropriate vocabulary from the standard; to identify and explain common misconceptions about mutations.

Your rubric will be based on this checklist:

  • block format (2 addresses, date, salutation, body is left justified, closing, proper grammar)
  • Identify and distinguish between the various types of mutations: point mutations and chromosomal mutations ( translocations, inversions, duplication, deletions, aneuploidy).
  • Identify and distinguish between the following causes of mutations: spontaneous, induced, and abnormal.
  • Identify and separate out false ideas of what genetic mutations are.

An additional resource

This website might be helpful.  It might just confuse the issues.  Use as you see fit.

Know Your Genes - Genes 101