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Surface Technology

Surface Technology

Author: creative biolabs

Surface Technology

Surface display technology indicates expressing the exogenous proteins/peptides on the surface of the host (from simplest virus to mammalian cells) by fusing the exogenous genes with membrane proteins genes or modifying proteins/peptide to be anchored by host surface elements. The principal advantage of this technology is that it provides an efficient approach to link the genotype and phenotype. By saving the protein purification process, it facilitates the research of proteins/peptides affinity for its targets and protein functions as enzymes. In practical, surface display is quite a useful tool in drug discovery by high throughput screening for the proteins/peptides binding to specific ligand and blocking their activities.

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